To start click on the Data Upload tab of the top navigation bar.
MIENTURNET is an easy-to-use web tool devised for:
- receiving in input a list of genes and inferring possible evidences (computational or experimental) of miRNA regulation based on a statistical analysis for over-representation of miRNA-target interactions;
- receiving in input a list of mature miRNAs and inferring possible evidences (computational or experimental) of their regulation on target genes based on a statistical analysis for over-representation of miRNA-target interactions.
MIENTURNET makes use of computationally predicted or experimentally validated miRNA-target interactions, for several organisms, downloaded from TargetScan and miRTarBase, respectively. MIENTURNET allows to visualize the results as miRNA-target interaction network.
Requirements and availability
MIENTURNET web tool is free and open to all users. It was tested with Firefox Version >62, Google Chrome Version >69, Safari Version 12.0.2, Internet Explorer Version 11.
How to cite MIENTURNET
If you use MIENTURNET, please cite:
- Licursi V et al. MIENTURNET: an interactive web tool for microRNA-target enrichment and network-based analysis. BMC Bioinformatics 20, 545 (2019) doi:10.1186/s12859-019-3105-x
[[HTML](https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-019-3105-x)] [[PDF](https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-019-3105-x)]
MIENTURNET was created using the shiny package from RStudio, it has been developed by Valerio Licursi1,2, Federica Conte1, Giulia Fiscon1 and Paola Paci1.
1Institute for Systems Analysis and Computer Science “Antonio Ruberti”, National Research Council, Rome, Italy
2Department of Biology and Biotechnology “Charles Darwin”, “Sapienza” University of Rome, Italy